Graphene based gene transfection

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August undefined, 2024

WebDec 4, 2024 · The objective of this study is to design a graphene-based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene … WebSep 15, 2012 · Efficient DNA delivery is essential for introducing new genes into living cells. However, effective virus-based systems carry risks and efficient synthetic systems that are non-toxic remain to be discovered. …

Carbon-based nanomaterials in gene therapy - ScienceDirect

WebDec 4, 2024 · The objective of this study is to design a graphene-based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene delivery system is developed using polyethylenimine (PEI) functionalized graphene oxide (GO) complex loaded with miR-7b overexpression plasmid. WebOct 13, 2014 · Graphene based biosensors make use of two strategies-1) probe molecule on graphene interacts with the analyte (FRET based ... Zhang S, Liu Z (2011) Graphene based gene transfection. Nanoscale 3: 1252-1257. Zhou L, Wang W, Tang J, Zhou JH, Jiang HJ, et al. (2011) Graphene oxide noncovalent photosensitizer and its anticancer … can i give dog food to cats

Graphene materials as 2D non-viral gene transfer vector platforms …

WebJul 30, 2024 · Methods: Graphene oxide/APTES was modified by spermine (GOAS) and characterized by FT-IR, DLS, SEM and AFM techniques. Then pEGFP-p53 was loaded on GOAS, transfected into cells and evaluated by fluorescent microscopy and gene expression techniques. Results: FT-IR data approved the GOAS sheet formation. Ninety percent of … WebJun 10, 2013 · Graphene oxide (GO) has been extensively explored in nanomedicine for its excellent physiochemical, electrical, and optical properties. ... 1 Jiangsu Key Laboratory for Carbon-Based, Functional Materials & Devices, ... remarkably enhanced plasmid DNA transfection efficiencies induced by the NIR laser are achieved using NGO-PEG-PEI as … WebApr 1, 2024 · Delivery of functional genes into stem cells shows great application prospect in DNA-based tissue engineering. However, comparing with epithelial cells and cancer cells, stem cells usually exhibit low gene transfection efficiency. To enhance the transfection efficiency, non-viral gene delivery in co … can i give herpes to my kids

Dr. Kishor sarkar - Assistant Professor - University of Calcutta

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WebWe conclude that modification of graphene-based nanoparticles with PEG and especially PEI provide better colloidal stability in cell medium, resulting in more uniform … WebJan 21, 2016 · During PhD work, I extensively involved on the development of chitosan based novel non-viral vectors for gene therapy application. I developed polyamidoamine (PAMAM) dendrimer conjugated chitosan copolymer through various chemical methods and showed very high transfection efficiency. All my research works published in reputed … fitvll reads blood pressureWebDec 1, 2013 · It can be summarized through these relevant studies that GO with suitable surface functionalization could serve as gene transfection vectors for in vitro and in vivo gene delivery. However, using graphene-based nanovectors as gene transfection vectors remains to be further explored. fit visio drawing to page

"WebJul 1, 2024 · Fig. 1. Illustration of various carbon-based structures (graphite sheets, graphene, nanotubes, fullerene, and nanodiamond) that are frequently used in medicine and biomedical applications. 2. Gene therapy and carbon structures. Gene therapy simply means using therapeutic nucleic acids as drugs to treat diseases [7]. " - Graphene based gene transfection

Graphene based gene transfection

WebJan 27, 2011 · Our results suggest graphene to be a novel gene delivery nano-vector with low cytotoxicity and high transfection efficiency, promising for future applications in non … WebNov 22, 2016 · The extraordinary physicochemical, optical and photothermal properties of graphene-based materials (GBMs) could offer two-dimensional components for the design of nucleic acid carrier systems.

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WebJan 10, 2014 · Successful gene therapy requires efficient and safe gene vectors that protect DNA from nuclease degradation as well as facilitate DNA uptake with high transfection efficiency [139], [140]. Graphene has been explored for applications in gene delivery, gene–drug co-delivery and protein delivery with good supportive literature available. WebJan 6, 2024 · Graphene oxide for transfection. ThermoFisher Scientific describes transfection as the process of artificially introducing nucleic acids – DNA or RNA – into cells, utilising means other than viral infection. A paper published in Nanoscale 2011 titled ‘Graphene based gene transfection’ showed that graphene oxide (“GO”) bound with ...

WebFeng, L., Zhang, S., & Liu, Z. (2011). Graphene based gene transfection. Nanoscale, 3(3), 1252. doi:10.1039/c0nr00680g WebGraphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for the first time we successfully use graphene as a non-toxic nano-vehicle for efficient gene transfection.

WebOur results suggest graphene to be a novel gene delivery nano-vector with low cytotoxicity and high transfection efficiency, promising for future applications in non-viral based … WebDec 4, 2024 · In treating osteoporotic ovariectomized mice, GO‐PEI‐miR‐7b significantly enhances bone mineral density, bone volume as well as bone vascularization through increasing CD31hiEmcnhi cell number. The objective of this study is to design a graphene‐based miRNA transfection drug delivery system for antiresorptive therapy. …

WebNov 22, 2016 · Graphene based gene transfection. Nanoscale 2011; 3: 1252–1257. Article CAS Google Scholar Prencipe G, Tabakman SM, Welsher K, Liu Z, Goodwin AP, Zhang L et al. PEG branched polymer for ...

WebAug 18, 2024 · Deoxyribonucleic acid (DNA) vaccines are a promising cancer immunotherapy approach. However, effective delivery of DNA to antigen-presenting cells (e.g., dendritic cells (DCs)) for the induction of an adaptive immune response is limited. Conventional DNA delivery via intramuscular, intradermal, and subcutaneous injection by … can i give heparin in armWebTo evaluate the transfection efficiency of NGQDs, we delivered mRNA into HeLa cells with NGQDs. As shown in Figure 4 a, the NGQDs formed complexes with mRNA at a 20:1 … can i give heartworm medicine lateWebApr 12, 2024 · Polymeric gene carriers target the nucleus and express their therapeusis through transcription and translation . Gene carriers are either viral vectors (retro-viruses and adenoviruses) or non-viral vectors. Viral vectors submit their genetic materials to the host cells and are known to attain greater transfection . 18.3.1.2 Polymeric Micelles fit vs cologuard testWebGraphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for the first time we … can i give honey to my catWebMar 1, 2011 · Graphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for … can i give hylands and tylenolWebVisualizing The Localization Of Transfection Complexes During Graphene Nanoparticle-Based Transfection Journal of Materials Chemistry B … can i give hotspot from laptopWebJan 23, 2024 · Recently graphene has been used in biomedical applications including DNA sequencing 10, biosensor development 11, and graphene-enhanced cell differentiation … can i give iacst again